Ulcer-healing drugs

A group of drugs that are used to treat or prevent peptic ulcers. The eradication of infection by treatment with antibiotic drugs and a drug to reduce acid secretion is now the preferred treatment for peptic ulceration. Ulcer-healing drugs work in several ways. H-receptor antagonists function by blocking the effects of histamine, an action that reduces acid secretion in the stomach, thereby promoting the healing of ulcers. Taking antacid drugs regularly may be effective in healing duodenal ulcers because the drugs neutralize excess acid. Omeprazole and misoprostol work by reducing acid secretion. Other ulcer-healing drugs, such as sucralfate, are believed to form a protective barrier over the ulcer, allowing healing of the underlying tissues to take place. The choice of ulcer-healing drug depends on the length of time symptoms have been present and the appearance of the ulcer during endoscopy. In many cases of recent onset, a course of acidblocking drugs or antacids will give rapid relief. Recurrent ulcers usually require treatment with antibiotic drugs.


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