Systemic sclerosis

Also known as scleroderma, a rare autoimmune disorder that can affect many organs and tissues, particularly the skin, arteries, kidneys, lungs, heart, gastrointestinal tract, and joints. The condition is 3 times as common in women and is most likely to appear between the age of 30 and 50. The number and severity of symptoms varies. The most common symptom is Raynaud’s phenomenon. Also common are changes in the skin, especially of the face and fingers, which becomes shiny, tight, and thickened, leading to difficulty with movements. Other parts of the body may also be affected, leading to difficulty in swallowing, shortness of breath, palpitations, high blood pressure, joint pain, or muscle weakness. Progression of scleroderma is often rapid in the first few years and then slows down or even stops. In a minority of people, degeneration is rapid, and leads to death from heart failure, respiratory failure, or kidney failure. There is no cure for scleroderma, but many of the symptoms can be relieved.

 

Online Medical Dictionary: Your essential reference to over 5000 medical terms.