Quinine

The oldest drug treatment for malaria. Quinine is now used mainly to treat strains of malaria that are resistant to other antimalarial drugs. Large doses are needed, and there is a high risk of adverse effects, including headache, nausea, hearing loss, ringing in the ears, and blurred vision. Quinine is commonly prescribed in low doses to help prevent leg cramps at night; adverse effects are rare.

 

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