Orlistat

An anti-obesity drug used with a slimming diet to treat severe obesity. Unlike appetite suppressants, orlistat acts on the gastrointestinal tract, preventing the digestion of fats by lipases (pancreatic enzymes). Instead of being absorbed, the fats pass out of the body in faeces. Side effects are gastrointestinal and can be minimized by reducing fat intake. Flatulence and faecal urgency are common. Deficiencies of fat-soluble vitamins may develop with prolonged use.

 

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