Behçet’s syndrome

A rare, multisystem disorder with recurrent mouth ulcers and genital ulcers and inflammation of the eyes, skin joints, blood vessels, brain, and intestines. The cause of Behçet’s syndrome is unknown, but it is strongly associated with a genetically determined histocompatability antigen, HLA-B51. Treatment is difficult and may require corticosteroid and immunosuppressant drugs. The condition often becomes long-term.


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